Table 1.
Sibling Correlations of Nine Autism Endophenotypes Tested for Familiality
Endophenotype | ADI-RItem | No. ofSib Pairs | Correlation | Pa |
Age at first word | A12 | 113 | .32 | .0006 |
Age at first phrase | A13 | 76 | .26 | .021 |
Difference between ages at first word and phrase | 74 | .23 | .05 | |
Language level | A19 | 155 | .03 | NS |
Repetitive and stereotyped behavior | DD total | 108 | .25 | .01 |
Circumscribed interests | A70a | 121 | .23 | .001 |
Unusual preoccupations | A71a | 154 | .14 | NS |
Repetitive use of objects | A72a | 143 | .02 | NS |
Difficulties with changes in routines or environment | A73a | 155 | .28 | .0001 |
NS = not significant.