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Aβ impairs spatial learning and memory in a dose-dependent manner. Rats received NH4OH or different concentrations of Aβ injection to the CA1 area and were subject to (a) water maze learning and (b) probe trial test. (c) Gel pattern and (d) analysis of protein expression of NR1, NR2A, NR2B, signal transducer and activator of transcription-1 (STAT1), and laminin β1 (LB1) after the probe trial test. Data are mean±SEM. *P<0.05, **P<0.01 and #P<0.001.
