Table 2.

White matter clusters demonstrating significant between-group differences at 3-year follow-up and corresponding pairwise comparisons (ps< 0.01, corrected); 3-year follow-up includes 54 individuals (BG+MJ, n = 21; BG, n = 17, CON, n = 16).

Anatomical Region	Volume (μl)	MNI Coordinates^*			Effect Size (Cohen’s d^†) CON > BG	Effect Size (Cohen’s d^†) CON > BG+MJ	Effect Size (Cohen’s d^†) BG+MJ > BG
Anatomical Region	Volume (μl)	X	Y	Z	Effect Size (Cohen’s d^†) CON > BG	Effect Size (Cohen’s d^†) CON > BG+MJ	Effect Size (Cohen’s d^†) BG+MJ > BG
1. Splenium (medial)	212	3.4	−34.9	16.5	1.6	1.7	-
2. Genu (medial)	59	4.4	27.7	2.6	1.3	1.5	-
3. (Inferior) Fronto-occipital Fasciculus (L)	52	−19.2	20.2	−7.9	1.0	1.5	-
4. Anterior Thalamic Radiations (R)	38	13.6	−12.8	14.2	1.3	1.4	-
5. Uncinate Fasciculus (L)	36	−26.0	28.5	−8.5	1.5	1.5	-
6. Uncinate Fasciculus (R)	34	36.5	47.2	−7.4	1.3	1.7	-
7. Superior Longitudinal Fasciculus (R)	32	46.5	−7.5	25.5	1.2	1.9	-
8. Anterior Limb Internal Capsule (L)	30	−22.3	20.3	3.4	1.2	1.2	-
9. Anterior Corona Radiata (R)	28	21.8	24.5	−4.5	1.4	1.5	-
10. Superior Corona Radiata (L)	27	−19.6	−10.0	4.8	1.3	1.3	-
11 Posterior Limb Internal Capsule (R)	26	19.2	−10.0	4.8	0.9	1.0	-
12. Superior Longitudinal Fasciculus (R)	25	31.3	−22.9	37.2	1.2	1.2	-
13 Anterior Corona Radiata (R)	24	19.5	35.7	16.9	1.1	1.1	-
14. Superior Longitudinal Fasciculus (R)	22	41.5	−7.0	28.9	1.3	0.9	-
15. Uncinate Fasciculus (R)	21	26.0	27.9	−10.1	1.3	-	1.2

Coordinates of the center of mass,

^†

Effect sizes computed from sample means and standard deviations