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. 1983 Oct;80(19):5898–5901. doi: 10.1073/pnas.80.19.5898

Chlamydomonas agglutinin is a hydroxyproline-rich glycoprotein

James B Cooper *, W Steven Adair *, Robert P Mecham †, John E Heuser ‡
PMCID: PMC390183  PMID: 16593377

Abstract

The mt+ sexual agglutinin from Chlamydomonas reinhardi is shown to contain ≈12% hydroxyproline, and two inhibitors of hydroxyproline formation, α,α′-dipyridyl and 3,4-dehydroproline, are shown to block the production of agglutinin activity in an in vivo bioassay system. These results indicate that the agglutinin glycoprotein may be related to a class of hydroxyproline-rich glycoproteins found in the extracellular matrix of higher plants, several of which have been shown to have lectin activity.

Keywords: cell-cell recognition, extracellular matrix, lectin, plant cell walls, prolyl hydroxylase

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Selected References

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