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. 2014 Feb 7;8:14. doi: 10.3389/fnins.2014.00014

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Copyright © 2014 Tupone, Madden and Morrison.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Inhibition of BAT thermogenesis through central modulatory areas. (A) Bilateral injection of the A1 adenosine receptor agonist, CHA, induces a rapid inhibition of the cold-evoked BAT SNA and reduces BAT temperature and expired CO₂. Modified from Tupone et al. (2013a). (B) Unilateral nanoinjection of the glucoprivic agent, 5-TG, into the VLM induces a rapid inhibition of cold-evoked BAT SNA and a fall in BAT temperature and expired CO₂. Modified from Madden (2012), Tupone et al. (2013a).