Table 3. Comparison of KS30, AT30, IS30, DS30 in all* PD patients versus controls.
Mean KS30 (95% CI) | Median AT30 (IQR) | Median IS30 (IQR) | Median DS30 (IQR) | ||
PD | 44.2 (40.9, 47.5) | 138.7 (100.5, 221.0) | 13813 (8744, 29857) | 1.042 (1.014, 1.147) | |
Controls | 60.3 (57.6, 63.0) | 97.3 (80.7, 131.2) | 6758 (4030, 16664) | 1.044 (1.013, 1.110) | |
p-value | <0.0001 | <0.0001 | 0.0003 | 0.45 | |
KS30 Sensitivity | AT30 Sensitivity | IS30 Sensitivity | |||
(cut-off) | (cut-off) | (cut-off) | |||
Specificity | 90% | 44.8%* (42.5) | 31.0%* (183) | 24.1%* (29954) | - |
Specificity | 85% | 50.0% (46.0) | 39.7% (156) | 29.3% (23527) | - |
Specificity | 80% | 56.9% (48.3) | 43.1% (149) | 36.2% (18527) | - |
PD, Parkinson's disease; KS30, kinesia score; AT30, akinesia time; IS30, incoordination score; DS30, dysmetria score; CI, confidence interval; IQR, interquartile range.
*If analyses were limited to include only patients that were ‘Off’ (n = 20) the sensitivities (and cut-off) for 90% specificity for KS30, AT30 and IS30 were 65% (43), 50% (175) and 55% (29373) respectively.