TABLE 2.
Unadjusted Prevalence of SSRI Use During Pregnancy
| SSRI Use | Boys and Girls | Boys Only | ||||
|---|---|---|---|---|---|---|
| ASD | DD | TD | ASD | DD | TD | |
| Total sample | ||||||
| n | 492 | 154 | 320 | 421 | 101 | 264 |
| Pregnancy, n (%) | 29 (5.9) | 8 (5.2) | 11 (3.4) | 25 (5.9)* | 6 (5.9) | 7 (2.7)* |
| Trimester 1 | 21 (4.3) | 4 (2.6) | 10 (3.1) | 18 (4.3) | 4 (4.0) | 6 (2.8) |
| Trimester 2 | 16 (3.3) | 7 (4.6) | 7 (2.2) | 14 (3.3) | 5 (5.0) | 4 (1.5) |
| Trimester 3a | 20 (4.1) | 8 (5.3) | 7 (2.2) | 18 (4.3)* | 6 (6.0)§ | 4 (1.5)*§ |
| Anxiety/mood disorder history subsetb | ||||||
| n | 122 | 40 | 67 | 102 | 29 | 50 |
| Pregnancy, n (%) | 28 (23) | 8 (20) | 10 (15) | 24 (24) | 6 (21) | 6 (12) |
| Trimester 1 | 21 (17) | 4 (10) | 9 (13) | 18 (18) | 4 (14) | 5 (10) |
| Trimester 2 | 16 (13) | 7 (18) | 7 (11) | 14 (14) | 5 (17) | 4 (8) |
| Trimester 3a | 19 (16) | 8 (20) | 7 (11) | 17 (17) | 6 (21) | 4 (8) |
P values were calculated by using likelihood ratio χ2 tests. Significant pairwise group differences (P ≤ .05): *ASD versus TD, §DD versus TD. ASD versus DD did not differ for any comparison.
a
Preterm delivery led to there being no third trimester for 3 participants in the ASD group (all boys), 2 participants in the DD group (1 boy, 1 girl) in the total sample, and for 1 participant in the ASD group (boy) in the subset.
b
Due to limited precision in the subgroup, percentages are reported without decimals.