Figure 6.
Structure of cHDMAPP in complex with B30.2 domain of BTN3A1. A) B30.2 is shown in ribbon format in orange, with pAg binding pocket residues shown as sticks. cHDMAPP is shown as sticks with spheres, and specific atoms are shown using standard coloring (carbon=yellow, red=oxygen, blue=nitrogen and orange=phosphate). Hydrogen-bonds ≤ 3.3Å are shown as yellow dashes. B) Omit map density of cHDMAPP is shown in teal scaled at 1σ. C) Positive density observed in the complex structure but missing in the apo structure as identified from the isomorphous difference map is shown in green scaled at 4σ.