Table 3.
Individual Human Genomes Sequenced to Date.*
| Genome† | Technology Used | Average Depth of Coverage | SNPs | ||
|---|---|---|---|---|---|
| Total | Known | Novel | |||
|
| |||||
| ×10−6 | |||||
|
| |||||
| Venter | Sanger method | 7.5 | 3.21 | 2.80 | 0.74 |
|
| |||||
| Watson | 454 Sequencing System (Roche) | 7.4 | 3.32 | 2.71 | 0.61 |
|
| |||||
| Chinese (YH) | Genome Analyzer (Illumina) | 36 | 3.07 | 2.67 | 0.39 |
|
| |||||
| African (NA18507) | Genome Analyzer (Illumina) | 40.6 | 3.61 | 2.72 | 0.88 |
|
| |||||
| African (NA18507) | SOLiD system (Applied Biosystems) | 17.9 | 3.86 | 3.13 | 0.73 |
|
| |||||
| Korean (SJK) | Genome Analyzer (Illumina) | 28.95 | 3.43 | 3.01 | 0.42 |
|
| |||||
| Korean (AK1) | Genome Analyzer (Illumina) | 27.8 | 3.45 | 2.88 | 0.57 |
|
| |||||
| Proband in this study | SOLiD system (Applied Biosystems) | 29.9 | 3.42 | 2.85 | 0.56 |
*
All genomes listed have a ploidy of 2n. SNP denotes single-nucleotide polymorphism.
†
The surname of the individual person or the ethnic group (and HapMap sample name, in parentheses) is given. The same African (Yoruban) sample NA18507 was sequenced twice, once with the use of the Genome Analyzer and once with the use of the SOLiD (Sequencing by Oligonucleotide Ligation and Detection) system.