Table 2.
Number of trials for agents with varying mechanisms of action
| Year registered | Symptomatic for cognition | Symptomatic for behavior | Disease-modifying small molecule | Disease-modifying immunotherapy | Therapeutic device | Stem cells | Total |
|---|---|---|---|---|---|---|---|
| 2002 |
1 |
3 |
0 |
1 |
0 |
0 |
5 |
| 2003 |
5 |
1 |
4 |
0 |
2 |
0 |
12 |
| 2004 |
5 |
2 |
6 |
0 |
1 |
0 |
14 |
| 2005 |
10 |
3 |
16 |
3 |
0 |
0 |
32 |
| 2006 |
12 |
1 |
8 |
4 |
0 |
0 |
25 |
| 2007 |
18 |
1 |
17 |
10 |
0 |
0 |
46 |
| 2008 |
23 |
1 |
18 |
15 |
4 |
0 |
61 |
| 2009 |
31 |
2 |
19 |
17 |
2 |
1 |
72 |
| 2010 |
11 |
2 |
23 |
13 |
2 |
0 |
51 |
| 2011 |
17 |
2 |
17 |
5 |
3 |
1 |
45 |
| 2012 |
18 |
4 |
17 |
8 |
2 |
1 |
50 |
| Total |
151 |
22 |
145 |
76 |
16 |
3 |
413 |
| Percent | 36.56 | 5.33 | 35.11 | 18.40 | 3.87 | 0.73 | 100 |