Table 1. CrAssphage ORFs with homology to known proteins or domains.
| ORF | Function of top hits | Species | Host phylum |
|---|---|---|---|
| orf00014 | Hypothetical protein | Phages | Ambiguous |
| orf00017 | Uracil-DNA glycosylase | Acetivibrio cellulolyticus | Firmicutes |
| orf00016 | DNA helicase | Francisella philomiragia | Proteobacteria |
| orf00018 | DNA polymerase | Labrenzia | Proteobacteria |
| orf00025 | DNA primase/helicase | Veillonella sp. | Firmicutes |
| orf00029 | DNA ligase | Erwinia phage | Proteobacteria |
| orf00031 | Deoxynucleoside monophosphate kinase | Enterobacteria phage | Proteobacteria |
| orf00032 | Baseplate hub | Aeromonas phage | Proteobacteria |
| orf00033 | Thymidylate synthase complementing protein ThyX | Prevotella sp. | Bacteroidetes |
| orf00035 | Hypothetical protein | Bacteroides sp. | Bacteroidetes |
| orf00037 | Phage/plasmid-related protein | Mucilaginibacter | Bacteroidetes |
| orf00038 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | Acinetobacter phage | Proteobacteria |
| orf00039 | Endonuclease | Paenibacillus sp. | Firmicutes |
| orf00040 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | Salmonella phage | Proteobacteria |
| orf00042 | Glutaredoxin/thioredoxin | Phages | Ambiguous |
| orf00047 | Hypothetical protein | Clostridium bolteae | Firmicutes |
| orf00050 | Plasmid replication protein domain | Firmicutes | Firmicutes |
| orf00052 | Phage-structural protein | Cellulophaga phage | Bacteroidetes |
| orf00053 | Phage-structural protein | Synechococcus phage | Cyanobacteria |
| orf00056 | Hypothetical protein | Escherichia phage | Proteobacteria |
| orf00065 | Hypothetical protein | Alistipes putredinis | Bacteroidetes |
| orf00066 | Phage-related protein | Escherichia phage | Proteobacteria |
| orf00070 | Predicted protein | Bacteroides sp. | Bacteroidetes |
| orf00071 | Predicted protein | Bacteroides sp. | Bacteroidetes |
| orf00072 | Hypothetical protein | Acinetobacter schindleri | Proteobacteria |
| orf00073 | Phage-related protein | Bacteroides stercoris | Bacteroidetes |
| orf00074 | Phage-structural protein, contains BACON domains | Bacteroides sp. | Bacteroidetes |
| orf00075 | Phage-structural protein | Mycobacterium phage | Actinobacteria |
| orf00077 | Recombination endonuclease sunbunit | Bacteroides vulgatus | Bacteroidetes |
| orf00076 | Phage-related protein | Desulfitobacterium hafniense | Firmicutes |
| orf00086 | Phage-structural protein | Veillonella sp. | Firmicutes |
| orf00088 | Phage-structural protein | Pseudomonas phage | Proteobacteria |
| orf00091 | Phage-structural protein | Cellulophaga phage | Bacteroidetes |
| orf00092 | Hypothetical protein | Veillonella sp. | Firmicutes |
| orf00093 | DNA helicase | Staphylococcus phage | Firmicutes |
| orf00094 | Endolysin | Marinilabilia salmonicolor | Bacteroidetes |
| orf00095 | Endolysin | Phage | Proteobacteria |
| orf00096 | Phage-related protein | Marinimicrobia sp. | Marinimicrobia |
| orf00102 | Plasmid replication protein domain | Firmicutes | Firmicutes |
ORF, open reading frame.
Function and taxonomy information of the hits are displayed. For details see Supplementary Data 2.