Table 1.
Cohort
Cohort | n | Diagnosis | Sequencing strategy | Age (y) mean ± SD (range) | Male (%) | APOE e4+ (%) |
---|---|---|---|---|---|---|
LOAD CASES | 141 | Clinical and neuropathologic | Exome sequencing | 76.7 (65–97) | 42 | 62 |
CONTROLS | 179 | Clinical and neuropathologic | Exome sequencing | 78 (60–102) | 55 | 40.7 |
Key: LOAD, late-onset Alzheimer's disease; SD, standard deviation.