. Author manuscript; available in PMC: 2014 Dec 8.

Published in final edited form as: Biochem Pharmacol. 2009 Nov 27;79(7):1007–1014. doi: 10.1016/j.bcp.2009.11.018

Table 1.

Initial and final body weights, blood glucose and glycosylated hemoglobin concentrations in control and diabetic rats maintained with and without PARP inhibitor treatment.

Variable	Control	Control + GPI-15,427	Diabetic	Diabetic + GPI-15427
Initial body weight, g	293 ± 3.4	296 ± 5.3	263 ± 4.2	264 ± 3.9
Final body weight, g	591 ± 23	545 ± 8	377 ± 19^**	362 ± 16^**
Initial blood glucose, mmol/l	5.58 ± 0.08	5.32 ± 0.1	22.7 ± 1.4^**	23.4 ± 0.4^**
Final blood glucose, mmol/l	5.99 ± 0.22	6.22 ± 0.11	18.4 ± 1^**	18.9 ± 2.6^**
HbA1c, %	5.34 ± 0.07	5.12 ± 0.06	11.8 ± 0.3^**	11.4 ± 0.5^**

Data are Means SEM, n = 8–10 per group.

^**

p < 0.01 vs controls.