Figure 5. Cells relying on protein scavenging for amino acid assimilation accumulate strictly proteinogenic amino acids.
KRPC cells were grown in amino acid-replete or amino acid-free medium and supplemented with physiological levels of albumin. (A) Fractional contribution of serum protein-derived carbon to intracellular amino acid pools. (B, C) Relative intracellular amino acid abundances. (D, E) Net uptake or excretion of amino acids into the medium. Data are means ± SE of n ≥ 3.