. Author manuscript; available in PMC: 2015 Feb 6.

Published in final edited form as: Future Oncol. 2014 Jan;10(1):107–122. doi: 10.2217/fon.13.168

Table 1.

Proportion of premenopausal women in each study and its associated risk ratio, sorted by increasing risk ratio.

Study (year)	Risk ratio	Premenopausal (%)	Genotype	DNA source	Ref.
*<20% premenopausal women*
Wegman et al. (2005)	0.52	0	*4	Tumor	[46]
Wegman et al. (2007)	0.69	0	*4	Tumor	[45]
Regan et al. (2012)	0.86	0	3 4 6 7 10 17 *41	Tumor	[50]
Rae et al. (2012)	0.99	0	2 3 4 6 10 17 *41	Tumor	[53]
Lash et al. (2011)	1.1	6	*4	Tumor	[42]
Schroth et al. (2009)	1.5	4	2 3 4 5 6 7 9 10 35 41	Tumor/blood	[56]
Goetz et al. (2013)	1.67	0	3 4 6 10 *41	FFPE tumor and normal tissue	[57]
Bijl et al. (2009)	2.27	0	*4	Blood	[61]
Damodaran et al. (2012)	12.37	9	2 4 5 10 *14	Blood	[74]
*≥20% premenopausal women*
Okishiro et al. (2009)	0.6	22	*10	Blood	[47]
Oesterreich et al. (2010)	0.65	^†	^†	^†	[48]
Nowell et al. (2005)	0.67	41	3 4 *5	FFPE tissue	[49]
Abraham et al. (2010)	0.93	50	4 5 6 9 10 41	Blood	[51]
Gor et al. (2010)	0.97	69	*4	Bone marrow/blood	[52]
Kim et al. (2010)	1	50	3 5 10 41	^†	[72]
Park et al. (2011)	1.14	>20	5 10 *41	Blood	[54]
Stingl et al. (2010)	1.16	49	*4	Blood	[55]
Sirachainan et al. (2012)	1.68	80	4 5 *10	Blood	[58]
Thompson et al. (2011)	1.96	21	2 3 4 5 6 7 9 10 35 41	Blood	[59]
Newman et al. (2008)	2.1	50	3 4 5 41	Blood	[60]
Morrow et al. (2012)	2.67	20	2 3 4 5 6 7 9 10 17 29 35 41 1xN 2xN	Blood	[44]
Ramón y Cajal et al. (2010)	3.4	43	2 3 4 5 6 7 9 10 20 35 *41	Blood	[62]
Sukasem et al. (2012)	3.88	63	2 5 10 36 41 4 *35	Blood	[63]
Xu et al. (2008)	4.7	24	*10	Blood	[64]
Teh et al. (2012)	6.24	35	4 5 10 14	Blood	[65]
Kiyotani et al. (2010)	6.48	52	4 5 6 10 14 21 36 41	Blood	[66]

^†

Data extracted from abstracts presented at the San Antonio Breast Cancer Symposium (TX, USA). The extent of genotyping, proportion of premenopausal women or DNA source could not be accurately estimated from the presented data.

FFPE: Formalin-fixed paraffin embedded.