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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Semin Radiat Oncol. 2015 Jan;25(1):4–10. doi: 10.1016/j.semradonc.2014.07.007

Figure 4.

Figure 4

Recurring waves of inflammation link radiation-induced tissue damage to anti-tumor immune activation with potentially excessive normal tissue damage. This is being offset by attempts to resolve the inflammatory lesion, to heal and to regulate immunity at the price of possible tumor immune escape. Black (tumor), red (inflammation), green (healing).