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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Biol Psychiatry. 2014 Sep 30;77(9):775–784. doi: 10.1016/j.biopsych.2014.09.017

Table 3. Most associated SNPsa with case status in primary analyses.

SNP Chr Clinical subgroup P.LRT OR L95.OR U95.OR GENE eQTLsb
rs11641365 16 ADOS CSS RRB much higher than SA 3.19e-07 2.06 1.54 2.76 CTU2
rs2393895 10 Higher ADOS social affect impairment 2.23e-07 1.91 1.48 2.47 ZNF365
rs868914 10 Higher ADOS social affect impairment 2.48e-07 1.68 1.37 2.07 ZNF365
rs1867503 3 ASD paternal model 4.18e-07 1.55 1.30 1.84 Regulates TOPBP1
rs1867504 3 ASD paternal model 4.18e-07 1.55 1.30 1.84 Regulates TOPBP1
rs1409313 10 ASD paternal model 4.01e-07 1.75 1.40 2.18 CUEDC2 Regulates C10orf26
rs4773054 13 ASD paternal model 5.25e-08 2.66 1.83 3.86
rs4773054 13 Autism paternal model 7.28e-08 2.9 1.91 4.39
a

p<5×10-7 and MAF>0.05 and positive effect of the rare allele

b

In cerebellum or parietal cortex according to scan database (www.scandb.org, (49))