Fig. 3.
Scheme of enzymes involved in glutathione synthesis and metabolism in the retina. AC, amacrine cell; BPC, bipolar cell; GC, ganglion cell; GCL, ganglion cell layer; γGCL, γglutamate cysteine ligase; G6PD, glucose-6-phosphate dehydrogenase; 6PG, 6-phosphogluconate; GPx, glutathione peroxidase; GR, glutathione reductase; GS, glutathione synthase; GSH, glutathione; HC, horizontal cell; INL, inner nuclear layer; IPL, inner plexiform layer; IOSP, inner and outer segments of photoreceptors; NF, nerve fibre; ONL, Outer nuclear layer; OPL, Outer plexiform layer; protein-S2, protein-S−S; protein (SH)2, protein-SH. RPE, retinal pigment epithelium; TR, thioredoxin reductase; TRX (SH)2, thioredoxin; TRX-S2, oxidised thioredoxin.