Table 1.
Selected genes altered in ASD, correlated with immune function.
Gene | Protein | Function |
---|---|---|
MET | Receptor tyrosine kinase (MET) | |
PTEN | Phosphatase and tensin homolog (PTEN) | |
TSC1 | Tuberous sclerosis complex-1 (TSC1) | Promote IL-12 increase and M2-macrophage conversion |
TSC2 | Tuberous sclerosis complex-2 (TSC2) | |
HLA-DRB4 | Major histocompatibility complex type II (MHC-II) | |
MIF | Macrophage migration inhibitory factor (MIF) | Guide and control of immune response |
C4B | Complement component 4B (C4B) |