Figure 6. Novel miR-33 mitochondrial target gene expression is regulated in vivo.
(A) Gene expression analysis of peritoneal macrophages isolated from western-fed Apoe-/- mice treated with control anti-miR or anti-miR33 for 8 weeks (from Figure 5). (B). Relative expression of miR-33a (red) and miR-33b (blue) as well as PGC-1α (PPARGC1A), SLC25A25, SLC25A23, NRF1 and TFAM in healthy arteries (Normal) or carotids from patients with atherosclerosis (Plaque) from the Biobank of Karolinska Endarterectomy (BiKE).