. Author manuscript; available in PMC: 2016 Oct 1.

Published in final edited form as: Clin Gastroenterol Hepatol. 2015 May 19;13(10):1730–1737.e9. doi: 10.1016/j.cgh.2015.05.023

Table 3.

Levels of selected metabolites in controls, early-stage and late -stage EAC cases in validation set

Metabolite	Controls		Cases				P value^b (Early stage vs Controls)	P value^b (Late stage vs Controls)	P value^b (Early stage vs late stage)
	N	Mean ^a(SD)	Early stage		Late stage
	N	Mean ^a(SD)	N	Mean ^a(SD)	N	Mean ^a(SD)
L-Proline	331	28.24( 8.64)	145	22.35( 5.89)	171	23.14( 7.48)	<.001	<.001	.682
3-Hydroxybutyrate	329	7.73( 9.92)	141	15.89(16.19)	168	19.89(18.97)	<.001	<.001	.071
D-Mannose	323	6.28( 3.61)	145	8.97( 3.36)	175	10.61( 4.79)	<.001	<.001	.005

Absolute mean values in ug/ml,

Wilcoxon-rank sum test

SD: standard deviation; ug/ml, microgram/milliliter; Significant P values in bold