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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: CNS Drugs. 2015 Sep;29(9):715–724. doi: 10.1007/s40263-015-0279-2

Figure 3.

Figure 3

Inhibition of placental maternal antibody transfer. A. Antibodies are transferred to the fetus during gestation to provide the neonate with a temporary immune system at birth. B. This process can be inhibited with the use of the neonatal Fc Receptor (FcRn) blockers in order to prevent the transfer of maternal anti-brain autoantibodies during critical periods of neurodevelopment. However, this would not be a specific process and would block all Immunoglobulin G (IgG).