Figure 3.
Inhibition of placental maternal antibody transfer. A. Antibodies are transferred to the fetus during gestation to provide the neonate with a temporary immune system at birth. B. This process can be inhibited with the use of the neonatal Fc Receptor (FcRn) blockers in order to prevent the transfer of maternal anti-brain autoantibodies during critical periods of neurodevelopment. However, this would not be a specific process and would block all Immunoglobulin G (IgG).