Figure 3.
Nrxn HET mice exhibit no alterations in exploratory behavior within a novel environment. Over the 30 min of the test, general ambulation was similar between wild type (WT; n = 24), Nrxn1α HET (n = 16), and Nrxn2α HET (n = 28) mice (a). During the experiment, mice were automatically tracked and their propensity for spending time in different zones was measured. All three genotypes spent a similar amount of time in the outer zone (b), the intermediate zone (c) and the center zone (d). HET = heterozygous; Nrxn1α = α-neurexin I; Nrxn2α = α-neurexin II.