Table 1.
Density of 5-HT terminals in substantia nigra compacta (SNc), reticulata (SNr) and in ventral tegmental area (VTA) nuclei: parabrachial pigmentosus (PBP), interfascicular (IF), rostral linear raphe (RLi) and paranigral (PN) of adult 6 month old mice. Numbers show mean + SEM. Five mice in each group were used.
| Mice group | nucleus | terminal density (No/mm2) |
|---|---|---|
| control | SNc | 2.629+0.742 |
| control | SNr | 3.526+0.420 |
| th(tk-)/th(tk-) | SNc | 2.484+0.052 |
| th(tk-)/th(tk-) | SNr | 5.916+0.257a |
| control | VTAPBP | 2.334+0.296 |
| control | VTAIF | 5.301+0.468 |
| control | VTARLi | 1.151+0.376 |
| control | VTAPN | 4.257+0.358 |
| th(tk-)/th(tk-) | VTAPBP | 5.487+0.624 b |
| th(tk-)/th(tk-) | VTAIF | 5.968+0.467 |
| th(tk-)/th(tk-) | VTARLi | 0.753+0.214 |
| th(tk-)/th(tk-) | VTAPN | 6.067+0.284 a |
Difference between control and th(tk-)/th(tk-) within the same nucleus:
a
p≤0.005;
b
p<0.00001 (ANOVA, LSD).