Table 2.

Baseline rDAm for sample enrichment: Results of sample enrichment using baseline rDAm (constructed using all the three imaging modalities T1 MRI, FDG and florbetapir) in a 2 year trial with outcome measures being MMSE, ADAS, MOCA, RAVLT, PsychMEM, Hippocampal Volume, CDR-SOB and DxConv. All estimates at significance level of 0.05 and 80% statistical power with treatment effect of 0.25. Second column shows sample estimates with no enrichment (i.e. all clinically-diagnosed MCI subjects included), followed by using MCI subjects from bottom 20%, 25%, 33% and 50% percentiles on rDAm scores respectively. For eachpercentile, the cutoff on rDAm scale is shown and sample sizes smaller than 700 are in bold.