Table 4.
Multivariate logistic unique associations with MDD and anxiety disorders
| Combined MDD and Anxiety Disorders | MDD Covarying Anxiety Onsets | Anxiety Disorders Covarying MDD Onsets | |||||||
|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||
| B(SE) | OR [95% CI] | p | B(SE) | OR [95% CI] | p | B(SE) | OR [95% CI] | p | |
| Model 1. | |||||||||
| Count of minor childhood adversities | .09(.13) | 1.09 [.84, 1.42] | 0.508 | −.02(.15) | .98 [.73, 1.32] | 0.894 | .12(.17) | 1.13 [.81, 1.57] | 0.476 |
| Count of major childhood adversities | .38(.14) | 1.46 [1.12, 1.90] | 0.006 | .25(.15) | 1.29 [.96, 1.72] | 0.092 | .43(.16) | 1.53 [1.13, 2.08] | 0.006 |
|
| |||||||||
| Model 2. | |||||||||
| Count of minor adolescent adversities | .26(.13) | 1.30 [1.00, 1.69] | 0.051 | .15(.15) | 1.16 [.87, 1.55] | 0.313 | .13(.17) | 1.14 [.81, 1.59] | 0.462 |
| Count of major adolescent adversities | .43(.14) | 1.54 [1.17, 2.02] | 0.002 | .41(.15) | 1.51 [1.12, 2.02] | 0.006 | .38(.16) | 1.46 [1.07, 2.00] | 0.017 |
|
| |||||||||
| Model 3. | |||||||||
| Multiplicative aggregate CTI score | .42(.24) | 1.52 [.95, 2.43] | 0.080 | .28(.27) | 1.32 [.78, 2.21] | 0.300 | .10(.28) | 1.10 [.63, 1.92] | 0.731 |
| Count of major childhood adversities | −.13(.22) | .88 [.57, 1.36] | 0.569 | −.28(.25) | .75 [.46, 1.23] | 0.257 | .29(.26) | 1.33 [.79, 2.23] | 0.278 |
| Count of major adolescent adversities | .30(.20) | 1.34 [.91, 1.98] | 0.134 | .46(.22) | 1.58 [1.03, 2.42] | 0.037 | .15(.23) | 1.16 [.74, 1.82] | 0.528 |
|
| |||||||||
| Model 4. | |||||||||
| Multiplicative aggregate CTI score | .25(.27) | 1.28 [.75, 2.18] | 0.367 | .24(.30) | 1.27 [.71, 2.27] | 0.426 | −.06(.32) | .94 [.50, 1.76] | 0.843 |
| Sum of severity: childhood adversities | −.11(.23) | .90 [.58, 1.40] | 0.642 | −.33(.25) | .72 [.44, 1.18] | 0.193 | .37(.27) | 1.45 [.85, 2.47] | 0.173 |
| Sum of severity: adolescent adversities | .48(.21) | 1.61 [1.07, 2.43] | 0.023 | .54(.23) | 1.71 [1.10, 2.67] | 0.018 | .24(.24) | 1.27 [.79, 2.05] | 0.325 |
Note: Analyses predicting first onsets of MDD covaried first onsets of anxiety disorders, and vice versa. Other covariates were SES and gender. All independent variables were standardized for ease of interpretation across indices. Significant associations (p ≤ .05) are bolded.