Table 1.
Patient Cohort Information
| Samples | Gender | Age | PMI | Neurological Diagnosis (Yrs) | Dementia (Yrs) | Plaque Density | Braak Score | Unified LB Stage | Pathology Summary |
|---|---|---|---|---|---|---|---|---|---|
| PD 1 | F | 80 | 7.5 | 11 | Moderate | III | lll. Brainstem/Limbic | Parkinson’s disease; Microscopic changes of Alzheimer’s disease but insufficient for diagnosis. | |
| PD 2 | F | 82 | 2.75 | 16 | Moderate | IV | lll. Brainstem/Limbic | Parkinson disease; Moderate microscopic lesions of Alzheimer’s disease (moderate plaques). | |
| PD 3 | M | 85 | 2.16 | 6 | Moderate | IV | llb. Limbic Predominant | Parkinson’s disease; Microscopic changes of Alzheimer’s disease. | |
| PD 4 | M | 72 | 10 | 17 | Sparse | II | llb. Limbic Predominant | Parkinson’s disease | |
| PD 5 | M | 70 | 1.83 | 12 | 3 | Zero | III | lll. Brainstem/Limbic | Parkinson Disease; Dementia (history) |
| PD 6 | F | 73 | 2.16 | 29 | 6 | Sparse | III | lV. Neocortical | Parkinson’s disease; Dementia (history) |
| PD 7 | M | 75 | 2.25 | 21 | 1 | Zero | III | lV. Neocortical | Parkinson’s disease; Dementia (history) |
| PD 8 | M | 77 | 4 | 11 | Sparse | III | lV. Neocortical | Parkinson’s disease | |
| PD 9 | F | 78 | 3.5 | 16 | 6 | Sparse | III | lV. Neocortical | Parkinson’s disease; Dementia (clinical history) |
| AD 1 | F | 82 | 4.5 | 9 | 9 | Moderate | IV | 0. No Lewy bodies | Alzheimer’s disease |
| AD 2 | F | 93 | 1.4 | 4 | 4 | Moderate | IV | 0. No Lewy bodies | Alzheimer’s Disease |
| AD 3 | M | 94 | 3 | 14 | 14 | Moderate | IV | 0. No Lewy bodies | Alzheimer’s Disease |
| AD 4 | M | 79 | 3.92 | 7 | 7 | Frequent | V | 0. No Lewy bodies | Alzheimer’s disease |
| AD 5 | F | 96 | 3 | 21 | 5 | Frequent | VI | 0. No Lewy bodies | Alzheimer’s disease |
| AD 6 | F | 87 | 3 | 5 | 5 | Frequent | V | 0. No Lewy bodies | Alzheimer’s disease |
| ND 1 | F | 87 | 2.83 | Zero | II | 0. No Lewy bodies | Control | ||
| ND 2 | F | 91 | 2 | Zero | II | 0. No Lewy bodies | Control; Entorhinal cortex neurofibrillary tangles consistent with normal aging. | ||
| ND 3 | F | 83 | 4.83 | Moderate | II | 0. No Lewy bodies | Control; Microscopic changes of Alzheimer’s disease but insufficient for diagnosis. | ||
| ND 4 | M | 89 | 2.5 | Moderate | II | 0. No Lewy bodies | Control; Microscopic changes of Alzheimer’s disease but insufficient for diagnosis. | ||
| ND 5 | M | 86 | 2.75 | Moderate | II | 0. No Lewy bodies | Control; Microscopic changes of Alzheimer’s disease but insufficient for diagnosis. |