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. Author manuscript; available in PMC: 2017 Jan 6.
Published in final edited form as: Neuron. 2015 Dec 10;89(1):147–162. doi: 10.1016/j.neuron.2015.11.023

Figure 4. Reduced NMDA Receptors Mediated Synaptic Transmission in Both R1117X+/+and InsG3680+/+ Shank3 Mutant Mice.

Figure 4

(A–C) Typical NMDA receptors mediated currents from striatal MSNs by stimulating corpus callosum and quantification. n = 16 neurons for wild-type; n = 18 neurons for R1117X+/+ from three pairs of littermates at 7 week’s age.

(D–F) Typical NMDA receptors mediated currents from striatal MSNs by stimulating corpus callosum and quantification. n = 14 neurons for wild-type; n = 12 neurons for InsG3680+/+ from three pairs of littermates at 8 week’s age. In both (C) and (F), data are presented as mean ± SEM. *p < 0.05; two-way ANOVA test.