Table 1.
Peptide-Conjugate Lipid Mediators from Human M1 and M2 Macrophages
| Lipid Mediator | Q1 | Q3 | M1 (pg/3 × 107 cells) | M2 (pg/3 × 107 cells) |
|---|---|---|---|---|
| PCTR1 | 650 | 231 | 1.5 ± 0.6 | 2.3 ± 0.4 |
| PCTR2 | 521 | 231 | 7.8 ± 1.9 | 30.5 ± 21.7 |
| PCTR3 | 465 | 231 | 14.2 ± 4.4 | 20.1 ± 9.2 |
| RCTR1 | 666 | 247 | 4.5 ± 2.3 | 11.8 ± 4.1 |
| RCTR2 | 537 | 247 | 4.7 ± 2.0 | 9.8 ± 5.6 |
| RCTR3 | 480 | 247 | 6.6 ± 0.3 | 15.5 ± 6.6 |
| MCTR1 | 650 | 191 | 4.5 ± 0.8 | 3.8 ± 1.6 |
| MCTR2 | 521 | 191 | 12.3 ± 3.4 | 5.4 ± 1.9 |
| MCTR3 | 465 | 191 | 6.6 ± 1.7 | 9.7 ± 2.7 |
| LTC4 | 626 | 189 | 47.7 ± 16.7 | 10.7 ± 0.5 |
| LTD4 | 497 | 189 | 33.1 ± 10.1 | 15.1 ± 6.5 |
| LTE4 | 440 | 189 | 47.1 ± 30.1 | 14.5 ± 4.0 |
Results are compared with LTs. n = 5. Data are expressed as means ± SEM.
LT, leukotriene; MCTR, maresin conjugates in tissue regeneration; PCTR, protectin conjugates in tissue regeneration; Q1, parent ion; Q3, diagnostic daughter ion; RCTR, resolving conjugates in tissue regeneration.