. 2016 Mar 23;65(7):1988–1995. doi: 10.2337/db15-1180

Table 2.

HRs for any IA, 2+ IA, and type 1 diabetes relative to weight or length/height z scores at various ages; months before IA, 2+ IA, or type 1 diabetes diagnosis; and time-varying model of growth up to 4 years of age

	Any IA				2+ IA				2+ IA to type 1 diabetes
Time	HR	95% CI	P value	FDR	HR	95% CI	P value	FDR	HR	95% CI	P value	FDR
Weight
12 months of age	1.16	1.06–1.27	0.001	0.008	1.21	1.08–1.35	0.001	0.008	0.98	0.81–1.18	0.81	0.81
24 months of age	1.10	1.01–1.20	0.03	0.091	1.18	1.06–1.32	0.004	0.021	0.96	0.80–1.16	0.69	0.69
36 months of age	1.07	0.98–1.17	0.15	0.17	1.13	1.01–1.28	0.04	0.091	0.97	0.80–1.18	0.79	0.79
Length/height
12 months of age	1.12	1.01–1.24	0.03	0.16	1.15	1.01–1.31	0.03	0.16	0.93	0.75–1.16	0.53	0.69
24 months of age	1.07	0.97–1.18	0.20	0.39	1.11	0.98–1.26	0.12	0.39	0.96	0.79–1.18	0.69	0.69
36 months of age	1.07	0.97–1.18	0.18	0.39	1.15	1.02–1.30	0.02	0.16	0.92	0.74–1.15	0.46	0.69
Weight
3 months prior	1.13	1.02–1.25	0.02	0.08	1.11	0.97–1.26	0.13	0.17
6 months prior	1.06	0.95–1.18	0.29	0.29	1.14	1.00–1.30	0.05	0.096
9 months prior	1.08	0.97–1.21	0.16	0.17	1.14	0.99–1.30	0.06	0.096
12 months prior	1.12	0.99–1.26	0.06	0.096	1.13	0.98–1.30	0.11	0.16
Length/height
3 months prior	1.03	0.92–1.15	0.66	0.70	1.09	0.94–1.26	0.24	0.39
6 months prior	1.06	0.95–1.19	0.32	0.39	1.09	0.94–1.26	0.25	0.39
9 months prior	0.98	0.87–1.11	0.80	0.80	1.07	0.92–1.25	0.37	0.42
12 months prior	1.07	0.94–1.22	0.32	0.39	1.11	0.95–1.31	0.19	0.39
Weight
Up to 4 years	1.11	1.01–1.23	0.04	0.09	1.10	0.96–1.25	0.16	0.17	0.79	0.61–1.04	0.09	0.15
Length/height
Up to 4 years	1.08	0.97–1.21	0.17	0.39	1.08	0.94–1.25	0.28	0.39	0.80	0.59–1.07	0.13	0.52

HRs adjusted for birth weight z score (for weight z score models) and birth length z scores (for length/height z score models), relation to type 1 proband, HLA-DR or -DQ genotype, and sex and stratified by country of residence. Boldface indicates statistical significance, FDR < 0.05. 2+ IA, multiple IA.