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TAFs derive predominantly from sessile precursors in a murine colon carcinoma model. Immunocompetent BM chimeric mice in which only the irradiated host (Left) or only the bone marrow (Right) expressed the COL-EGFP transgene were injected with Cerulean-expressing MC38 colon carcinoma in a dorsal window. EGFP-expressing cells were mainly observed when COL-EGFP was expressed in the irradiated host.
