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. 2016 Aug 19;5(8):e98. doi: 10.1038/cti.2016.51

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Copyright © 2016 The Author(s)

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

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Distribution of human and murine MAIT cells in tissues. The frequency of MAIT cells (defined either by MR1 tetramers or as CD161⁺⁺Vα7.2⁺ T cells) within T cells, as has been described in the indicated tissues of mice and humans. MAIT cells are enriched within peripheral organs including the liver and gut, whereas they are less enriched within lymphoid organs. However, MAIT cells are much more abundant in humans compared with common laboratory strains of mice.