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. Author manuscript; available in PMC: 2016 Dec 15.
Published in final edited form as: Mol Psychiatry. 2013 May 21;19(5):568–572. doi: 10.1038/mp.2013.59

Table 1.

Disease-related CNVs observed in patients with COS

NSB ID Chr. band Start (hg18) Stop (hg18) Size (kb) Type Duplicated or deleted genes Inheritance Disease Reported in 2008
1358a 2p25.3 1 591 064 1 836 375 245 Dup   2 Mother SCZ Yes
534a 2p25.3 1 720 133 1 827 317 107 Dup   2 Unknown SCZ Yes
581 2p16.3 50 025 162 50 136 989 112 Del   2 Unknown SCZ, ASD Yes
534a 8q11.2 53 550 992 54 043 684 493 Dup   3 Unknown ID No
885 10q22.3 81 415 378 81 588 866 173 Del   5 De novo ID No
448 15q11.2 18 818 086 20 203 694 1386 Del 24 Unknown SCZ, ID, Epi No
1358a 15q11.2 20 203 694 20 778 963 575 Del 13 Mother SCZ, ID, Epi No
1546a 15q13.3 30 238 780 30 620 951 382 Del 26 De novo SCZ, ASD, ID, Epi No
498 15q13.3 30 238 780 30 713 368 475 Del 30 Mother SCZ, ASD, ID, Epi No
481 16p12.1 21 498 074 21 946 841 449 Del   7 Father ID No
676a 16p11.2 29 502 984 30 107 306 604 Dup 15 Father SCZ, ASD Yes
2011 16p11.2 29 782 436 30 227 808 445 Dup 34 Father SCZ, ASD Yes
1546a 17q21.3 41 321 621 41 706 070 384 Dup   4 Father ID No
1275 22q11.2 17 092 563 20 077 678 2985 Del 49 De novo SCZ, ID No
1220 22q11.2 17 224 632 19 842 333 2618 Del 48 De novo SCZ, ID No
537 22q11.2 17 257 787 19 855 248 2597 Del 46 Unknown SCZ, ID No
1804 22q11.2 17 257 787 19 963 350 2706 Del 47 De novo SCZ, ID No
3169 22q11.2 17 269 794 20 128 199 2858 Del 55 De novo SCZ, ID No
676a 22q13.3 47 903 228 49 557 485 1654 Dup   4 De novo ASD No

Abbreviations: ASD, autism spectrum disorders; COS, childhood onset schizophrenia; CNV, copy number variants; Epi, epilepsy; ID, intellectual disability; SCZ, schizophrenia.

a

Individuals with two events.