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. 2017 May 1;524:56–67. doi: 10.1016/j.ab.2017.01.009

Fig. 2.

Fig. 2

Early steps of the “acidic” bile acid biosynthesis pathway generating 3β-HCA and 3β,7α-diHCA, two cholestenoic acids regulating the survival and death of motor neurons. Full stereochemistry is shown only for the initial sterol in the pathway. Systematic names given in parenthesis. Enzymes are indicated where known.