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. 2017 May 1;524:56–67. doi: 10.1016/j.ab.2017.01.009

Fig. 3.

Fig. 3

Synthesis and metabolism of oxysterol modulators of Hh signalling. Some of the oxysterols are prevalent in patients suffering from NP-C disease or SLOS. Full stereochemistry is shown only for the initial sterols in the pathways. Systematic names given in parenthesis. Enzymes are indicated where known. Broken arrows indicate postulated pathway and enzyme.