TABLE 1.
Comparison of genomic features of CoV-HKU1 and other coronaviruses and amino acid identities
Coronavirusa | Genome featuresc
|
Pairwise amino acid identity (%)b
|
||||||||
---|---|---|---|---|---|---|---|---|---|---|
Size (bases) | G+C content | 3CLpro | Pol | Hel | HE | S | E | M | N | |
Group 1 | ||||||||||
HCoV-229E | 27,317 | 0.38 | 45 | 54 | 55 | NPe | 31 | 26 | 35 | 28 |
PEDV | 28,033 | 0.42 | 44 | 56 | 55 | NP | 30 | 34 | 37 | 37 |
PTGV | 28,586 | 0.38 | 45 | 57 | 57 | NP | 32 | 34 | 37 | 27 |
CCoV | NAc | NA | NA | NA | NA | NP | 31 | 32 | 36 | 27 |
HCoV-NL63 | 27,553 | 0.34 | 43 | 54 | 54 | NP | 30 | 28 | 32 | 28 |
Group 2 | ||||||||||
CoV-HKU1 | 29,926 | 0.32 | nad | na | na | na | na | na | na | na |
HCoV-OC43 | 30,738 | 0.37 | 82 | 87 | 88 | 57 | 60 | 54 | 76 | 58 |
MHV | 31,357 | 0.42 | 85 | 90 | 89 | 50 | 61 | 57 | 84 | 68 |
BCoV | 31,028 | 0.37 | 84 | 88 | 88 | 56 | 61 | 55 | 76 | 57 |
SDAV | NA | NA | NA | NA | NA | 50 | 61 | 60 | 77 | 62 |
ECoV | NA | NA | NA | NA | NA | 53 | 61 | 56 | 78 | 59 |
PHEV | NA | NA | NA | NA | NA | 54 | 61 | 54 | 77 | 57 |
Group 3 | ||||||||||
IBV | 27,608 | 0.38 | 41 | 60 | 57 | NP | 32 | 28 | 38 | 27 |
SARS-CoV | 29,751 | 0.41 | 48 | 65 | 63 | NP | 33 | 27 | 34 | 31 |
HCoV-229E, human coronavirus 229E; PEDV, porcine epidemic diarrhea virus; PTGV, porcine transmissible gastroenteritis virus; CCoV, canine enteric coronavirus; HCoV-NL63, human coronavirus NL63; HCoV-OC43, human coronavirus OC43; MHV, murine hepatitis virus; BCoV, bovine coronavirus; SDAV, rat sialodacryoadenitis coronavirus; ECoV, equine coronavirus NC99; PHEV, porcine hemagglutinating encephalomyelitis virus; IBV, infectious bronchitis virus; SARS-CoV, SARS coronavirus.
Amino acid identities between the predicted chymotrypsin-like protease (3CLpro), RNA-dependent RNA polymerase (Pol), helicase (Hel), hemagglutinin-esterase (HE), spike (S), envelope (E), membrane (M), and nucleocapsid (N) proteins of CoV-HKU1 and the corresponding proteins of other coronaviruses.
NA, not available.
na, not applicable.
NP, not present.