Figure 2.
IL-10 regulates CD163, but not IL-6, in COPD MDMs generated in the presence of SAA. A, B) Gene expression of IL-6 (A) and CD163 (B) was compared between MDMs generated from healthy controls and subjects with COPD. C, D) Spearman correlation between IL-10 and IL-6 (C) and IL-10 and CD163 (D) in SAA-induced MDMs from patients with COPD. E, F) No relationship was observed between systemic serum SAA levels and expression of IL-6 (E) or CD163 (F). Data represent n = 6 for control and n = 7 for COPD individual blood samples. *P < 0.05 vs. vehicle-treated MDM expression; #P < 0.05; Spearman test.