Table 1. Clinical and demographic characteristics.
| Group | Number of seizures | Number of patients | Number of females (%) | Age (years, mean ± SD) | Duration of epilepsy (years, mean ± SD) | Number of patients off medication pre-study (%) |
|---|---|---|---|---|---|---|
| Patients without seizures | 0 | 54 | 27 (50%) | 10·6 ± 3·7 | 4·0 ± 3·7 | 6 (11%) |
| Patients with seizures | 1032 | 39 | 23 (59%) | 9·9 ± 3·1 | 3·0 ± 2·5 | 14 (36%) |
| Comparison* | P= 1·000 | P=0·329 | P= 0·128 | P=0 005 | ||
| Spared seizures total | 139 | 21 | 11 (52%) | 10·6 ± 3·2 | 2·9 ± 0·9 | 6 (29%) |
| Impaired seizures total | 160 | 27 | 17 (63%) | 100 ± 31 | 3·2 ± 2·6 | 11 (41%) |
| Comparison* | P=0·560 | P=0·541 | P=0·691 | P=0·544 | ||
| Spared seizures fMRI | 93 | 17 | 8 (47%) | 10·7 ± 3·3 | 3·3 ± 21 | 5 (29%) |
| Impaired seizures fMRI | 112 | 22 | 16 (73%) | 10·2 ± 3·3 | 3·8 ± 2·3 | 8 (36%) |
| Comparison* | P=0 184 | P=0·631 | P=0·554 | P=0·740 | ||
| Spared seizures HD-EEG | 30 | 5 | 2 (40%) | 13·5 ± 3·6 | 3·3 ± 2·9 | 4 (80%) |
| Impaired seizures HD-EEG | 26 | 8 | 5 (63%) | 110 ± 4·5 | 2·8 ± 2·8 | 5 (63%) |
| Comparison* | P=0·592 | P=0·303 | P=0·752 | P= 1·000 |
Spared and impaired seizures total groups include all seizures used for analyses in Figures 2, 4, 5 and 6. Spared and impaired seizures fMRI or HD-EEG groups include all seizures used for Figures 4, 5 and 6.
*
Two-tailed t-test was used for age and duration of epilepsy; Fisher's exact test was used for % female and % off medication pre-study.
See also Table S1 for additional characteristics of individual patients with seizures.