Table 10.
Materials and their concentrations used for interference tests for tau protein assay by utilizing the tau reagent with IMR. The concentration of tau protein in each sample is 100 pg/ml. The matrix is PBS solution. The detected tau protein concentrations of each sample are listed. Using the tau protein concentration of the pure Tau-PBS sample (sample No. 1) as a reference, the Mean % Recovery values of the tau protein concentration for other samples are calculated and listed in the right-most column.
| Sample No. | Interfering material | Concentration | Measured tau protein concentration (pg/ml) | Mean % Recovery |
|---|---|---|---|---|
| 1 | None | — | 99.85 | — |
| 2 | Hemoglobin | 10000 μg/ml | 99.21 | 99.4% |
| 3 | Conjugated bilirubin | 600 μg/ml | 91.67 | 91.8% |
| 4 | Intra lipid | 30000 μg/ml | 108.51 | 108.7% |
| 5 | Uric acid | 200 μg/ml | 91.67 | 91.8% |
| 6 | Rheumatoid factor | 500 IU/ml | 93.48 | 93.6% |
| 7 | Albumin | 60000 μg/ml | 95.80 | 95.9% |
| 8 | Acetylsalicylic acid | 500 μg/ml | 106.13 | 106.3% |
| 9 | Ascorbic acid | 300 μg/ml | 107.31 | 107.5% |
| 10 | Ampicillin sodium | 1000 μg/ml | 107.43 | 107.6% |
| 11 | Quetiapine Fumarate | 100 ng/ml | 107.61 | 107.8% |
| 12 | Galantamine hydrobromide | 90 ng/ml | 108.51 | 108.7% |
| 13 | Rivastigmine hydrogen tartrate | 100 ng/ml | 107.25 | 107.4% |
| 14 | Donepezil Hydrochloride | 1000 ng/ml | 100.45 | 100.6% |
| 15 | Memantine Hydrochloride | 150 ng/ml | 108.75 | 108.9% |