. 2017 Oct 25;106(Suppl 6):1606S–1614S. doi: 10.3945/ajcn.117.155887

TABLE 3.

Response of iron status indicators to a depletion of body iron compartments with and without concomitant inflammation and to an overload of body iron compartments¹

Compartment	Indicator	IDA	ACD	IDA + ACD	Overload
Stored iron	SF	Reduced	Normal to increased	Reduced to normal	Increased
Transport iron	Iron	Reduced	Reduced	Reduced	Increased
	Transferrin	Increased	Reduced	Reduced	Reduced
	TSAT	Reduced	Reduced	Reduced	Increased
	EP	Increased	Increased	Increased	Reduced
	sTfR	Increased	Normal	Normal to increased	Normal
Functional iron	Hemoglobin	Reduced	Reduced	Reduced	Normal
Inflammatory response	NA	Normal	Increased	Increased	NA

ACD, anemia of chronic disease; EP, erythrocyte protoporphyrin; IDA, iron deficiency anemia; IDA + ACD, combined iron deficiency anemia and anemia of chronic disease; NA, not applicable; SF, serum ferritin; sTfR, soluble transferrin receptor; TSAT, transferrin saturation.