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. Author manuscript; available in PMC: 2018 Nov 9.
Published in final edited form as: Nature. 2017 Nov 1;551(7679):227–231. doi: 10.1038/nature24470

Extended Data Figure 8. Loss of Kctd13 does not affect cortical layer thickness or cell counts in E15 embryos.

Extended Data Figure 8

a, b, No differences in Tbr1-stained cortical layer thickness (a) or cell counts (b) were observed in E15 pups; Tbr1 thickness: P = 0.893 (WT n = 7; HET n = 6 ; KO n = 5); cell count: P = 0.304 (WT n = 7; HET n = 6; KO n = 5). c, d, No differences in Tbr2-stained cortical layer thickness (c) or cell counts (d) were observed among Kctd13 WT and mutant E15 pups; TBR2 thickness: P = 0.543 (WT n = 6; HET n = 5; KO n = 3); cell count: P = 0.353 (WT n = 6; HET n = 5; KO n = 3). e, f, No differences in Tuj1-stained cortical layer thickness (e) or the intensity of staining (f) were observed among Kctd13 WT and mutant E15 pups; Tuj1 thickness: P = 0.428 (WT n = 7; HET n = 5; KO n = 6); Tuj1 intensity: P = 0.091 (WT n = 7; HET n = 5; KO n = 6). g, i, Representative images of Kctd13 WT, HET, KO cortical Tbr1, Tbr2, and Tuj1 with DAPI co-stain; scale bar, 50 μm. Values represent mean ± s.e.m.