Figure 7. mTOR inhibition promotes CD8+ T cell mediated anti-tumor immunity.
(A–B) Naive or 72 h conditioned OT-I cells were adoptively transferred into BL/6 recipients. Mice were inoculated with 2 × 106 E.G7 tumor cells, 24h post adoptive transfer of OT-I cells (A); tumor size (mm3) over time from tumor inoculation (B); Percent of tumor free survival over time from tumor inoculation. A representative of two independent experiments is shown.