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. 2017 Apr 21;66(1):1–32. doi: 10.15585/mmwr.rr6601a1

TABLE 4. CDC novel influenza virus pandemic intervals.

Intervals Indicators
Investigation: Investigation of novel influenza cases
This interval is indicated by the identification of an animal case of influenza A subtype with potential implications for human health or identification of a human case of novel influenza A anywhere in the world.
Recognition: Recognition of potential for ongoing transmission
This interval is indicated by an increasing number of cases or clusters of novel influenza A in humans and by virus characteristics indicating potential for ongoing human-to-human transmission anywhere in the world.
Initiation: Initiation of the pandemic wave
This interval is indicated by confirmation of cases of novel influenza A in humans and demonstration of efficient and sustained human-to-human transmission anywhere in the world.
Acceleration: Acceleration of the pandemic wave
This interval is indicated by an increasing rate of novel influenza A cases identified nationally, indicating establishment in the country.
Deceleration: Deceleration of the pandemic wave
This interval is indicated by decreasing rates of novel influenza A infection.
Preparation: Preparation for a future pandemic wave This interval is indicated by sporadic cases of novel influenza A infection and surveillance rates returning to baseline.

Source: Holloway R, Rasmussen SA, Zaza S, Cox NJ, Jernigan DB; Influenza Pandemic Framework Workgroup. Updated preparedness and response framework for influenza pandemics. MMWR Recomm Rep 2014;63(No. RR-6).