Table 3.
Cross-sectional cognitive test scores by outcome groups (mean and SD values)
| Tests | Outcome group
|
ApoE group
|
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Baseline
|
Follow-up
|
Baseline
|
Follow-up
|
|||||||||
| Non-Dec | Dec | P | Non-Dec | Dec | P | E4− | E4+ | P | E4− | E4+ | P | |
| Para-I | 7.4 ± 1.8 | 6.2 ± 2.5 | 7.4 ± 2.3 | 5.4 ± 2.4 | * | 6.9 ± 2.4 | 6.7 ± 2.0 | 6.9 ± 2.2 | 5.4 ± 2.9 | |||
| Para-D | 9.5 ± 2.6 | 7.4 ± 3.5 | 8.4 ± 2.1 | 6.0 ± 4.0 | * | 8.7 ± 3.6 | 8.0 ± 2.5 | 8.1 ± 3.1 | 5.6 ± 3.4 | + | ||
| Assc-I | 5.5 ± 2.9 | 4.1 ± 3.6 | 6.7 ± 3.0 | 4.3 ± 3.5 | 5.1 ± 3.3 | 4.4 ± 3.3 | 6.2 ± 3.3 | 4.2 ± 3.4 | ||||
| Assc-D | 6.5 ± 3.4 | 4.7 ± 3.5 | 7.8 ± 2.8 | 4.1 ± 3.4 | + | 6.2 ± 3.2 | 4.2 ± 3.8 | 6.8 ± 3.2 | 4.4 ± 3.9 | |||
| Designs | 7.5 ± 1.6 | 5.6 ± 2.5 | + | 7.8 ± 2.3 | 4.2 ± 3.0 | + | 6.6 ± 2.2 | 6.6 ± 2.7 | 6.1 ± 3.0 | 6.2 ± 3.8 | ||
| DSST | 58.2 ± 9.3 | 48.9 ± 15.0 | 59.2 ± 10.4 | 48.8 ± 9.9 | * | 53.8 ± 14.2 | 53.5 ± 10.9 | 54.7 ± 10.5 | 53.0 ± 13.4 | |||
| Object | 55.6 ± 5.1 | 47.0 ± 18.0 | 57.7 ± 3.6 | 46.9 ± 16.6 | * | 50.9 ± 15.7 | 53.6 ± 4.5 | 54.9 ± 7.4 | 43.7 ± 21.9 | |||
| Shop-I | 7.1 ± 1.3 | 6.3 ± 1.6 | 7.8 ± 1.7 | 5.6 ± 2.1 | + | 6.9 ± 1.6 | 6.4 ± 1.2 | 7.2 ± 2.0 | 5.6 ± 2.4 | |||
| Shop-D | 8.7 ± 1.3 | 7.7 ± 2.1 | 9.3 ± 1.0 | 6.8 ± 3.0 | + | 8.5 ± 1.7 | 7.8 ± 1.8 | 8.7 ± 1.7 | 6.8 ± 3.4 | * | ||
| Recog | 16.8 ± 10.0 | 14.6 ± 9.0 | 15.7 ± 9.7 | 13.8 ± 8.3 | 16.1 ± 8.9 | 15.2 ± 11.0 | 16.1 ± 8.9 | 12.4 ± 9.0 | ||||
Dec, decline; I, immediate recall; D, delayed recall; Para, paragraph; Assc, paired associate; DSST, digit symbol substitution test; Object, object naming; Shop, shopping list; Recog, visual recognition; E4+, carrier; E4−, noncarrier;
*
, P ≤ 0.05; +, P ≤ 0.01.