Table 2.
Association between the rates of all significant inflammatory biomarkers simultaneously entered in the model (slope of change of biomarkers over time) and the rate of renal function (slope of eGFR over time).
Slope of eGFR over 9 yearsa |
||
---|---|---|
β̂ | p | |
TNFα-R1 | −0.25(0.03) | <0.001 |
IL-6 | −0.03(0.03) | 0.50 |
HS_CRP | −0.01(0.02) | 0.49 |
DM | −0.08(0.05) | 0.57 |
SBP | −0.05(0.054) | 0.02 |
Slope of eGFR: slope of estimated rate of glomerular filtration, the model is adjusted for baseline eGFR, age, sex, marital status, education, site of study, cancer, NSAIDs use, calf muscle area, SBP, new-onset DM, baseline systolic blood pressure (SBP); slopes of eGFR and all inflammatory biomarkers, calf muscle area and SBP are standardized; β̂: standardized beta regression coefficient, presented per SD unit increase; SD: standard deviation