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A young (a) and a senescent (b) eMV. AOM: antioxidant machinery; PPP: pentose phosphate pathway; GNG: gluconeogenesis; ROS: reactive oxygen species; DH: dehydrogenases; BCAA: branched-chain amino acids. Note that the senescent eMV has larger enzymatic machineries, uses more metabolites to feed them, and also has a higher capacity for ROS scavenging.
