Table 5.
Influence of Race on association between FTP SUVR and amyloid
| Data type | Predictor | Estimate | SE | t value | p value | Adj. p value (10 tests) |
|---|---|---|---|---|---|---|
| CP SUVR
|
||||||
| pvc | PiB DVR | 0.030 | 0.261 | 0.114 | 0.910 | >1.000 |
| non-pvc | PiB DVR | 0.004 | 0.088 | 0.046 | 0.963 | >1.000 |
| HC SUVR
|
||||||
| pvc | PiB DVR | 0.194 | 0.073 | 2.671 | 0.008 | 0.085 |
| non-pvc | PiB DVR | 0.120 | 0.051 | 2.331 | 0.021 | 0.212 |
| residual HC SUVR
|
||||||
| pvc | PiB DVR | 0.188 | 0.056 | 3.335 | 0.001 | 0.011 |
| non-pvc | PiB DVR | 0.118 | 0.034 | 3.459 | 0.001 | 0.007 |
| HC SUVR
|
||||||
| pvc | PiB DVR * Race | −0.204 | 0.301 | −0.677 | 0.499 | >1.000 |
| non-pvc | PiB DVR * Race | 0.114 | 0.213 | 0.536 | 0.593 | >1.000 |
| residual HC SUVR
|
||||||
| pvc | PiB DVR * Race | −0.532 | 0.230 | −2.317 | 0.022 | 0.219 |
| non-pvc | PiB DVR * Race | −0.176 | 0.141 | −1.248 | 0.214 | >1.000 |
Adj. p, p values adjusted for multiple comparison using the Bonferroni method; CP, choroid plexus; HC, hip-pocampus; PiB DVR, 11C-Pittsburg Compound B Distribution Volume Ratio; pvc, partial volume correction using geometric transfer matrix method; SE, standard error; SUVR, standardized uptake value ratio. NOTE: CDR > 0 participants were included in the sample used here (N = 147). Cerebellar cortex was used as reference for all SUVR shown. Separate multiple linear regression models were run. All models covarying for race, age, sex, and education. Bold values indicate significant association between FTP measurements in the CP and nearby ROI (p < 0.05).