Table 1. Association between ABCA7 rs4147929:G>A or CD33 rs3865444:C>A and LOAD in unadjusted, adjusted and APOE-Ɛ4 stratified models.
| GENE marker | Unadjusted model | Adjusted (sex and APOE- ε4) |
Adjusted (age, sex and APOE-ε4) |
Stratification per APOE-ε4 | |
|---|---|---|---|---|---|
| Carriers | Non- Carriers | ||||
|
ABCA7 rs4147929 |
OR =1.148 CI =1.036 – 1.27 p = 0.008 |
OR = 1.190 CI = 1.070 – 1.324 p = 0.0013 |
OR = 1.175 CI = 0.94 – 1.47 p = 0.1546 |
OR = 1.225 CI = 1.006 – 1.492 p = 0.043 |
OR = 1.167 CI = 1.028 – 1.324 p = 0.017 |
|
CD33 rs3865444 |
OR = 0.986 CI = 0.897 – 1.084 p = 0.771 |
OR = 0.976 CI = 0.885-1.076 p = 0.6287 |
OR = 0.920 CI = 0.750 –1.127 p = 0.4182 |
OR = 1.157 CI = 0.970 – 1.380 p = 0.104 |
OR = 0.899 CI = 0.797 – 1.014 p = 0.083 |
Abbreviations: LOAD, Late Onset Alzheimer’s disease; OR, Odds Ratio; CI, Confidence Interval.