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. Author manuscript; available in PMC: 2018 Jun 4.
Published in final edited form as: Neurobiol Aging. 2016 Nov 21;51:148–155. doi: 10.1016/j.neurobiolaging.2016.11.007

Figure 1. Results of ROC analysis using the 12-metabolite panel.

Figure 1

This figure shows plots of SN vs NCs ROC analysis using the 12-metabolite panel in targeted discovery (a) and validation (b) phases and application of the 12-metabolite panel to the external aMCI/AD (c) and ConverterpreAD (d) samples. 95% confidence intervals shaded in blue. Crosshair on ROC plot represents optimal ROC threshold. SN = Supernormal, NCs = Normal control for supernormal sample; aMCI/AD = amnestic mild cognitive impairment and Alzheimer’s disease; ConverterpreAD = Preclinical AD; NCo = Normal control for ConverterpreAD and aMCI/AD samples.